Kontaktujte nás | Jazyk: čeština English
dc.title | Obesity in cases undergoing the surgical procedure of lung lobectomy: risk or benefit? | en |
dc.contributor.author | Tulinský, Lubomír | |
dc.contributor.author | Sengul, Ilker | |
dc.contributor.author | Ihnát, Peter | |
dc.contributor.author | Ostruszka, Petr | |
dc.contributor.author | Toman, Daniel | |
dc.contributor.author | Guňková, Petra | |
dc.contributor.author | Pelikán, Anton | |
dc.contributor.author | Sengul, Demet | |
dc.relation.ispartof | Revista da Associacao Medica Brasileira | |
dc.identifier.issn | 0104-4230 Scopus Sources, Sherpa/RoMEO, JCR | |
dc.identifier.issn | 1806-9282 Scopus Sources, Sherpa/RoMEO, JCR | |
dc.date.issued | 2022 | |
utb.relation.volume | 68 | |
utb.relation.issue | 8 | |
dc.citation.spage | 1090 | |
dc.citation.epage | 1095 | |
dc.type | article | |
dc.language.iso | en | |
dc.publisher | Associacao Medica Brasileira | |
dc.identifier.doi | 10.1590/1806-9282.20220526 | |
dc.relation.uri | https://www.scielo.br/j/ramb/a/qzCwhFnf6QtnLBJFfpGTmqM/?lang=en | |
dc.relation.uri | https://www.scielo.br/j/ramb/a/qzCwhFnf6QtnLBJFfpGTmqM/?format=pdf&lang=en | |
dc.subject | obesity | en |
dc.subject | lung lobectomy | en |
dc.subject | risk factor | en |
dc.subject | obesity paradox | en |
dc.subject | thoracoscopy | en |
dc.description.abstract | OBJECTIVE: The aim of the study was to evaluate the effect of body mass index on patients' short-term results following lung lobectomy. METHODS: In this retrospective study, we compared the perioperative and short-term postoperative results of obese (BMI >= 30 kg/m2) versus non -obese patients (BMI<30 kg/m2) who underwent anatomical lung resection for cancer. The two groups had the same distribution of input risk factors and the same ratio of surgical approaches (thoracoscopy vs. thoracotomy).RESULTS: The study included a total of 144 patients: 48 obese and 96 non-obese patients. Both groups had the same ratio of thoracoscopic vs. thoracotomy approach (50/50%), and were comparable in terms of demographics and clinical data. The g roups did not significantly differ in the frequency of perioperative or postoperative complications. Postoperative morbidity was higher among non-obese patients (34.4 vs. 27.1%), but this difference was not statistically significant (p=0.053). Hospital stay was similar in both study groups (p=0.100). Surgery time was significantly longer among obese patients (p=0.133). Postoperative mortality was comparable between the study groups (p=0.167).CONCLUSIONS: Obesity does not increase the frequency of perioperative and postoperative complications in patients after lung lobectomy. The slightly better results in obese patients suggest that obesity may have some protective role. | en |
utb.faculty | Faculty of Humanities | |
dc.identifier.uri | http://hdl.handle.net/10563/1011146 | |
utb.identifier.obdid | 43883866 | |
utb.identifier.scopus | 2-s2.0-85138265229 | |
utb.identifier.wok | 000865466400024 | |
utb.identifier.pubmed | 36134838 | |
utb.identifier.coden | RMDBA | |
utb.source | j-scopus | |
dc.date.accessioned | 2022-10-05T13:13:10Z | |
dc.date.available | 2022-10-05T13:13:10Z | |
dc.description.sponsorship | MZ ČR – RVO-FNOs/2019 | |
dc.description.sponsorship | University Hospital Ostrava in the Czech Republic; [MZ ?]; [RVO-FNOs/2019] | |
dc.rights | Attribution-NonCommercial 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.rights.access | openAccess | |
utb.contributor.internalauthor | Pelikán, Anton | |
utb.fulltext.affiliation | Lubomír Tulinský1,2 https://orcid.org/0000-0003-3100-5990 , Ilker Sengul3,4 https://orcid.org/0000-0001-5217-0755 ,Peter Ihnát1,2 https://orcid.org/0000-0001-6353-6257 , Petr Ostruszka1,2 https://orcid.org/0000-0003-2986-2619 , Daniel Toman1,2 https://orcid.org/0000-0002-6627-3162 , Petra Guňková1,2 https://orcid.org/0000-0002-1177-5157 , Anton Pelikán1,2,5 https://orcid.org/0000-0002-4302-9298 , Demet Sengul6* https://orcid.org/0000-0002-0416-0621 1 University Hospital Ostrava, Department of Surgery – Ostrava, Czech Republic 2 University of Ostrava, Faculty of Medicine, Department of Surgical Studies – Ostrava, Czech Republic. 3 Giresun University, Faculty of Medicine, Division of Endocrine Surgery – Giresun, Turkey. 4 Giresun University, Faculty of Medicine, Department of Surgery – Giresun, Turkey. 5 Tomas Bata University in Zlin, Faculty of Humanities – Zlin, Czech Republic 6 Giresun University, Faculty of Medicine, Department of Pathology – Giresun, Turkey. * Corresponding author: [email protected] | |
utb.fulltext.dates | Received 05 Apr 2022 Accepted 11 Apr 2022 Publication in this collection 19 Sept 2022 Date of issue Aug 2022 | |
utb.fulltext.references | 1 Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-49. https://doi.org/10.3322/caac.21660 2 Israelsson LA, Jonsson T. Overweight and healing of midline incisions: the importance of suture technique. Eur J Surg. 1997;163(3):175-80. PMID: 9085058 3 Bamgbade OA, Rutter TW, Nafiu OO, Dorje P. Postoperative complications in obese and nonobese patients. World J Surg. 2007;31(3):556-60. https://doi.org/10.1007/s00268-006-0305-0 4 Choban PS, Heckler R, Burge JC, Flancbaum L. Increased incidence of nosocomial infections in obese surgical patients. Am Surg. 1995;61(11):1001-5. PMID: 7486411 5 Brandt M. Severe obesity does not adversely affect perioperative mortality and morbidity in coronary artery bypass surgery. Eur J Cardiothorac Surg. 2001;19(5):662-6. https://doi.org/10.1016/s1010-7940(01)00647-9 6 Wigfield CH, Lindsey JD, Muñoz A, Chopra PS, Edwards NM, Love RB. Is extreme obesity a risk factor for cardiac surgery? An analysis of patients with a BMI≥40. Eur J Cardiothorac Surg. 2006;29(49):434-40. https://doi.org/10.1016/j.ejcts.2006.01.016 7 Kuduvalli M, Grayson A, Oo A, Fabri B, Rashid A. Risk of morbidity and in-hospital mortality in obese patients undergoing coronary artery bypass surgery. Eur J Cardiothorac Surg. 2002;22(5):787-93. https://doi.org/10.1016/s1010-7940(02)00448-7 8 Petrelli F, Cortellini A, Indini A, Tomasello G, Ghidini M, Nigro O, et al. Obesity paradox in patients with cancer: A systematic review and meta-analysis of 6,320,365 patients. MedRxiv. 2020. https://doi.org/10.1101/2020.04.28.20082800 9 Seely AJ, Ivanovic J, Threader J, Al-Hussaini A, Al-Shehab DX, Ramsay T, et al. Systematic classification of morbidity and mortality after thoracic surgery. Ann Thorac Surg. 2010;90(3):936-42. https://doi.org/10.1016/j.athoracsur.2010.05.014 10 Stamou SC, Nussbaum M, Stiegel RM, Reames MK, Skipper ER, Robicsek F, et al. Effect of body mass index on outcomes after cardiac surgery: is there an obesity paradox? Ann Thorac Surg. 2011;91:42-7. https://doi.org/10.1016/j.athoracsur.2010.08.047 11 Le-Bert G, Santana O, Pineda AM, Zamora C, Lamas GA, Lamelas J. The obesity paradox in elderly obese patients undergoing coronary artery bypass surgery. Interact Cardiovasc Thorac Surg. 2011;13(2):124-7. https://doi.org/10.1510/icvts.2010.256677 12 Levin NW, Handelman GJ, Coresh J, Port FK, Kaysen GA. Reverse epidemiology: a confusing, confounding, and inaccurate term. Semin Dial. 2007;20(6):586-92. https://doi.org/10.1111/j.1525-139X.2007.00366.x 13 Fleischmann E, Teal N, Dudley J, May W, Bower JD, Salahudeen AK. Influence of excess weight on mortality and hospital stay in 1346 hemodialysis patients. Kidney Int. 1999;55(4):1560-7. https://doi.org/10.1046/j.1523-1755.1999.00389.x 14 Hainer V, Aldhoon-Hainerova I. Obesity paradox does exist. Diabetes Care. 2013;36(Suppl2):S276-81. https://doi.org/10.2337/dcS13-2023 15 Wang L, Liu W, He X, Chen Y, Lu J, Liu K, et al. Association of overweight and obesity with patient mortality after acute myocardial infarction: a meta-analysis of prospective studies. Int J Obes (Lond). 2015;40(2):220-8. https://doi.org/10.1038/ijo.2015.176 16 Gruberg L, Weissman NJ, Waksman R, Fuchs S, Deible R, Pinnow EE, et al. The impact of obesity on the short-term andlong-term outcomes after percutaneous coronary intervention: the obesity paradox? J Am Coll Cardiol. 2002;39:578-84. https://doi.org/10.1016/s0735-1097(01)01802-2 17 Vemmos K, Ntaios G, Spengos K, Savvari P, Vemmou A, Pappa T, et al. Association between obesity and mortality after acute first-ever stroke: the obesity-stroke paradox. Stroke. 2010;42(1):30-6. https://doi.org/10.1161/STROKEAHA.110.593434 18 Julien JBS, Aldrich MC, Sheng S, Deppen SA, Burfeind Jr WR, Putnam JB, et al. Obesity increases operating room time for lobectomy in the society of thoracic surgeons database. Ann Thorac Surg. 2012;94(6):1841-7. https://doi.org/10.1016/j.athoracsur.2012.08.006 19 Onaitis MW, Petersen RP, Balderson SS, Toloza E, Burfeind WR, Harpole Jr DH, et al. Thoracoscopic lobectomy is a safe and versatile procedure: experience with 500 consecutive patients. Ann Surg. 2006;244:420-5. https://doi.org/10.1097/01.sla.0000234892.79056.63 20 Paul S, Altorki NK, Sheng S, Lee PC, Harpole DH, Onaitis MW, et al. Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: a propensity-matched analysis from the STS database. J Thorac Cardiovasc Surg. 2010;139(2):366-78. https://doi.org/10.1016/j.jtcvs.2009.08.026 21 Smith PW, Wang H, Gazoni LM, Shen KR, Daniel TM, Jones DR. Obesity does not increase complications after anatomic resection for non-small cell lung cancer. Ann Thorac Surg. 2007;84(4):1098-106. https://doi.org/10.1016/j.athoracsur.2007.04.033 22 Petrella F, Radice D, Borri A, Galetta D, Gasparri R, Solli P, et al. The impact of preoperative body mass index on respiratory complications after pneumonectomy for non-small-cell lung cancer. Results from a series of 154 consecutive standard pneumonectomies. Eur J Cardiothorac Surg. 2011;39(5):738-44. https://doi.org/10.1016/j.ejcts.2010.09.007 23 Launer H, Nguyen DV, Cooke DT. National perioperative outcomes of pulmonary lobectomy for cancer in the obese patient: a propensity score matched analysis. J Thorac Cardiovasc Surg. 2013;145(5):1312-8. https://doi.org/10.1016/j.jtcvs.2012.10.012 24 Childers DK, Allison DB. The ‘obesity paradox’: a parsimonious explanation for relations among obesity, mortality rate and aging? Int J Obes. 2010;34(8):1231-8. https://doi.org/10.1038/ijo.2010.71 25 Al-Ameri M, Bergman P, Franco-Cereceda A, Sartipy U. Video-assisted thoracoscopic versus open thoracotomy lobectomy: a Swedish nationwide cohort study. J Thorac Dis. 2018;10(6):3499-506. https://doi.org/10.21037/jtd.2018.05.177 | |
utb.fulltext.sponsorship | This study was supported by the University Hospital Ostrava in the Czech Republic under grant number MZ ČR – RVO-FNOs/2019. | |
utb.wos.affiliation | [Tulinsky, Lubomir; Ihnat, Peter; Ostruszka, Petr; Toman, Daniel; Gunkova, Petra; Pelikan, Anton] Univ Hosp Ostrava, Dept Surg, Ostrava, Czech Republic; [Tulinsky, Lubomir; Ihnat, Peter; Ostruszka, Petr; Toman, Daniel; Gunkova, Petra; Pelikan, Anton] Univ Ostrava, Fac Med, Dept Surg Studies, Ostrava, Czech Republic; [Sengul, Ilker] Giresun Univ, Fac Med, Div Endocrine Surg, Giresun, Turkey; [Sengul, Ilker] Giresun Univ, Fac Med, Dept Surg, Giresun, Turkey; [Pelikan, Anton] Tomas Bata Univ Zlin, Fac Humanities, Zlin, Czech Republic; [Sengul, Demet] Giresun Univ, Fac Med, Dept Pathol, Giresun, Turkey | |
utb.scopus.affiliation | University Hospital Ostrava, Department of Surgery, Ostrava, Czech Republic; University of Ostrava, Faculty of Medicine, Department of Surgical Studies, Ostrava, Czech Republic; Giresun University, Faculty of Medicine, Division of Endocrine Surgery, Giresun, Turkey; Giresun University, Faculty of Medicine, Department of Surgery, Giresun, Turkey; Tomas Bata University in Zlin, Faculty of Humanities, Zlin, Czech Republic; Giresun University, Faculty of Medicine, Department of Pathology, Giresun, Turkey | |
utb.fulltext.projects | MZ ČR – RVO-FNOs/2019 | |
utb.fulltext.faculty | Faculty of Humanities | |
utb.fulltext.ou | - |