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dc.title | Hyaluronan hydrogels modified by glycinated Kraft lignin: Morphology, swelling, viscoelastic properties and biocompatibility | en |
dc.contributor.author | Musilová, Lenka | |
dc.contributor.author | Mráček, Aleš | |
dc.contributor.author | Kovalčík, Adriána | |
dc.contributor.author | Smolka, Petr | |
dc.contributor.author | Minařík, Antonín | |
dc.contributor.author | Humpolíček, Petr | |
dc.contributor.author | Vícha, Robert | |
dc.contributor.author | Ponížil, Petr | |
dc.relation.ispartof | Carbohydrate Polymers | |
dc.identifier.issn | 0144-8617 Scopus Sources, Sherpa/RoMEO, JCR | |
dc.date.issued | 2018 | |
utb.relation.volume | 181 | |
dc.citation.spage | 394 | |
dc.citation.epage | 403 | |
dc.type | article | |
dc.language.iso | en | |
dc.publisher | Elsevier | |
dc.identifier.doi | 10.1016/j.carbpol.2017.10.048 | |
dc.relation.uri | https://www.sciencedirect.com/science/article/pii/S0144861717311918 | |
dc.subject | Hyaluronan | en |
dc.subject | Lignin | en |
dc.subject | Hydrogel | en |
dc.subject | Swelling behaviour | en |
dc.subject | Mechanical properties | en |
dc.subject | Biocompatibility of hydrogels | en |
dc.description.abstract | Effects of the addition of water soluble glycinated Kraft lignin (WS/KL) on the mechanical stability and biocompatibility of hyaluronan (NaHy) hydrogels were evaluated in this work. Water soluble lignin was obtained by the modification of Kraft lignin via a Mannich reaction. It was found that WS/KL is highly compatible with hyaluronan due to its improved water solubility, which favours its use in designing new advanced composite hydrogels. The effects of the concentration of WS/KL on morphological, swelling and creep/recovery behaviours of hyaluronan hydrogels were investigated. It was detected that the creep resistance and creep recovery of NaHy hydrogels was improved by the incorporation of up to 3% (w/w) of WS/KL. In contrast, the swelling capacity of hydrogels was decreased. The cytotoxicity tests proved that glycinated KL lignin limits the viability of cells only slightly, and the final hyaluronan/lignin hydrogels were non-toxic materials. © 2017 Elsevier Ltd | en |
utb.faculty | University Institute | |
utb.faculty | Faculty of Technology | |
dc.identifier.uri | http://hdl.handle.net/10563/1007572 | |
utb.identifier.obdid | 43878223 | |
utb.identifier.scopus | 2-s2.0-85032697086 | |
utb.identifier.wok | 000418661000047 | |
utb.identifier.coden | CAPOD | |
utb.source | j-scopus | |
dc.date.accessioned | 2018-01-15T16:31:29Z | |
dc.date.available | 2018-01-15T16:31:29Z | |
dc.description.sponsorship | 17-05095S, GACR, Grantová Agentura České Republiky; CZ.1.05/2.1.00/03.0111, MŠMT, Ministerstvo Školství, Mládeže a Tělovýchovy | |
dc.description.sponsorship | Operational Program Research and Development Fund (ERDF); national budget of the Czech Republic [CZ.1.05/2.1.00/03.0111]; Ministry of Education, Youth and Sports of the Czech Republic - Program NPU I [LO1504]; TBU in Zlin [IGA/FT/2013/015, IGA/FT/2014/018]; Czech Science Foundation [17-05095S]; project, "Materials Research Centre -Sustainability and Development" of the Ministery of Education, Youth and Sport of the Czech Republic [LO1211] | |
utb.ou | Centre of Polymer Systems | |
utb.contributor.internalauthor | Musilová, Lenka | |
utb.contributor.internalauthor | Mráček, Aleš | |
utb.contributor.internalauthor | Smolka, Petr | |
utb.contributor.internalauthor | Minařík, Antonín | |
utb.contributor.internalauthor | Humpolíček, Petr | |
utb.contributor.internalauthor | Vícha, Robert | |
utb.contributor.internalauthor | Ponížil, Petr | |
utb.fulltext.affiliation | Lenka Musilová a,d, Aleš Mráček a,d⁎, Adriana Kovalcik b,c⁎⁎, Petr Smolka a,d, Antonín Minařík a,d, Petr Humpolíček a, Robert Vícha e, Petr Ponížil a,d a Centre of Polymer Systems, Tomas Bata University in Zlín, třída Tomáše Bati 5678, 760 01 Zlín, Czech Republic b Institute for Chemistry and Technology of Materials, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria c Department of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkynova 118, 612 00 Brno, Czech Republic d Department of Physics and Materials Engineering, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka 275, 760 01 Zlín, Czech Republic e Department of Chemistry, Faculty of Technology, Tomas Bata University in Zlín, nám T.G. Masaryka 275, 760 01 Zlín, Czech Republic * Corresponding author at: Department of Physics and Materials Engineering, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka 275, 760 01 Zlín, Czech Republic ⁎⁎ Corresponding author at: Institute of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkynova 118, 612 00 Brno, Czech Republic E-mail addresses: [email protected] (A. Mráček), [email protected] (A. Kovalcik). | |
utb.fulltext.dates | Received 11 August 2017 Received in revised form 6 September 2017 Accepted 11 October 2017 Available online 27 October 2017 | |
utb.wos.affiliation | [Musilova, Lenka; Mracek, Ales; Smolka, Petr; Minarik, Antonin; Humpolicek, Petr; Ponizil, Petr] Tomas Bata Univ Zlin, Ctr Polymer Syst, Trida Tomase Bati 5678, Zlin 76001, Czech Republic; [Kovalcik, Adriana] Graz Univ Technol, Inst Chem & Technol Mat, Stremayrgasse 9, A-8010 Graz, Austria; [Kovalcik, Adriana] Brno Univ Technol, Dept Food Chem & Biotechnol, Fac Chem, Purkynova 118, Brno 61200, Czech Republic; [Musilova, Lenka; Mracek, Ales; Smolka, Petr; Minarik, Antonin; Ponizil, Petr] Tomas Bata Univ Zlin, Fac Technol, Dept Phys & Mat Engn, Nam TG Masaryka 275, Zlin 76001, Czech Republic; [Vicha, Robert] Tomas Bata Univ Zlin, Fac Technol, Dept Chem, Nam TG Masaryka 275, Zlin 76001, Czech Republic | |
utb.scopus.affiliation | Centre of Polymer Systems, Tomas Bata University in Zlín, třída Tomáše Bati 5678, Zlín, Czech Republic; Institute for Chemistry and Technology of Materials, Graz University of Technology, Stremayrgasse 9, Graz, Austria; Department of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkynova 118, Brno, Czech Republic; Department of Physics and Materials Engineering, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka 275, Zlín, Czech Republic; Department of Chemistry, Faculty of Technology, Tomas Bata University in Zlín, nám T.G. Masaryka 275, Zlín, Czech Republic | |
utb.fulltext.faculty | Faculty of Technology | |
utb.fulltext.faculty | Faculty of Technology | |
utb.fulltext.faculty | Faculty of Technology | |
utb.fulltext.faculty | Faculty of Technology | |
utb.fulltext.faculty | Faculty of Technology | |
utb.fulltext.faculty | Faculty of Technology | |
utb.fulltext.ou | Centre of Polymer Systems | |
utb.fulltext.ou | Department of Physics and Materials Engineering | |
utb.fulltext.ou | Centre of Polymer Systems | |
utb.fulltext.ou | Department of Physics and Materials Engineering | |
utb.fulltext.ou | Centre of Polymer Systems | |
utb.fulltext.ou | Department of Physics and Materials Engineering | |
utb.fulltext.ou | Centre of Polymer Systems | |
utb.fulltext.ou | Department of Physics and Materials Engineering | |
utb.fulltext.ou | Centre of Polymer Systems | |
utb.fulltext.ou | Department of Chemistry | |
utb.fulltext.ou | Centre of Polymer Systems | |
utb.fulltext.ou | Department of Physics and Materials Engineering |