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Hyaluronan hydrogels modified by glycinated Kraft lignin: Morphology, swelling, viscoelastic properties and biocompatibility

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dc.title Hyaluronan hydrogels modified by glycinated Kraft lignin: Morphology, swelling, viscoelastic properties and biocompatibility en
dc.contributor.author Musilová, Lenka
dc.contributor.author Mráček, Aleš
dc.contributor.author Kovalčík, Adriána
dc.contributor.author Smolka, Petr
dc.contributor.author Minařík, Antonín
dc.contributor.author Humpolíček, Petr
dc.contributor.author Vícha, Robert
dc.contributor.author Ponížil, Petr
dc.relation.ispartof Carbohydrate Polymers
dc.identifier.issn 0144-8617 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2018
utb.relation.volume 181
dc.citation.spage 394
dc.citation.epage 403
dc.type article
dc.language.iso en
dc.publisher Elsevier
dc.identifier.doi 10.1016/j.carbpol.2017.10.048
dc.relation.uri https://www.sciencedirect.com/science/article/pii/S0144861717311918
dc.subject Hyaluronan en
dc.subject Lignin en
dc.subject Hydrogel en
dc.subject Swelling behaviour en
dc.subject Mechanical properties en
dc.subject Biocompatibility of hydrogels en
dc.description.abstract Effects of the addition of water soluble glycinated Kraft lignin (WS/KL) on the mechanical stability and biocompatibility of hyaluronan (NaHy) hydrogels were evaluated in this work. Water soluble lignin was obtained by the modification of Kraft lignin via a Mannich reaction. It was found that WS/KL is highly compatible with hyaluronan due to its improved water solubility, which favours its use in designing new advanced composite hydrogels. The effects of the concentration of WS/KL on morphological, swelling and creep/recovery behaviours of hyaluronan hydrogels were investigated. It was detected that the creep resistance and creep recovery of NaHy hydrogels was improved by the incorporation of up to 3% (w/w) of WS/KL. In contrast, the swelling capacity of hydrogels was decreased. The cytotoxicity tests proved that glycinated KL lignin limits the viability of cells only slightly, and the final hyaluronan/lignin hydrogels were non-toxic materials. © 2017 Elsevier Ltd en
utb.faculty University Institute
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1007572
utb.identifier.obdid 43878223
utb.identifier.scopus 2-s2.0-85032697086
utb.identifier.wok 000418661000047
utb.identifier.coden CAPOD
utb.source j-scopus
dc.date.accessioned 2018-01-15T16:31:29Z
dc.date.available 2018-01-15T16:31:29Z
dc.description.sponsorship 17-05095S, GACR, Grantová Agentura České Republiky; CZ.1.05/2.1.00/03.0111, MŠMT, Ministerstvo Školství, Mládeže a Tělovýchovy
dc.description.sponsorship Operational Program Research and Development Fund (ERDF); national budget of the Czech Republic [CZ.1.05/2.1.00/03.0111]; Ministry of Education, Youth and Sports of the Czech Republic - Program NPU I [LO1504]; TBU in Zlin [IGA/FT/2013/015, IGA/FT/2014/018]; Czech Science Foundation [17-05095S]; project, "Materials Research Centre -Sustainability and Development" of the Ministery of Education, Youth and Sport of the Czech Republic [LO1211]
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Musilová, Lenka
utb.contributor.internalauthor Mráček, Aleš
utb.contributor.internalauthor Smolka, Petr
utb.contributor.internalauthor Minařík, Antonín
utb.contributor.internalauthor Humpolíček, Petr
utb.contributor.internalauthor Vícha, Robert
utb.contributor.internalauthor Ponížil, Petr
utb.fulltext.affiliation Lenka Musilová a,d, Aleš Mráček a,d⁎, Adriana Kovalcik b,c⁎⁎, Petr Smolka a,d, Antonín Minařík a,d, Petr Humpolíček a, Robert Vícha e, Petr Ponížil a,d a Centre of Polymer Systems, Tomas Bata University in Zlín, třída Tomáše Bati 5678, 760 01 Zlín, Czech Republic b Institute for Chemistry and Technology of Materials, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria c Department of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkynova 118, 612 00 Brno, Czech Republic d Department of Physics and Materials Engineering, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka 275, 760 01 Zlín, Czech Republic e Department of Chemistry, Faculty of Technology, Tomas Bata University in Zlín, nám T.G. Masaryka 275, 760 01 Zlín, Czech Republic * Corresponding author at: Department of Physics and Materials Engineering, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka 275, 760 01 Zlín, Czech Republic ⁎⁎ Corresponding author at: Institute of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkynova 118, 612 00 Brno, Czech Republic E-mail addresses: [email protected] (A. Mráček), [email protected] (A. Kovalcik).
utb.fulltext.dates Received 11 August 2017 Received in revised form 6 September 2017 Accepted 11 October 2017 Available online 27 October 2017
utb.wos.affiliation [Musilova, Lenka; Mracek, Ales; Smolka, Petr; Minarik, Antonin; Humpolicek, Petr; Ponizil, Petr] Tomas Bata Univ Zlin, Ctr Polymer Syst, Trida Tomase Bati 5678, Zlin 76001, Czech Republic; [Kovalcik, Adriana] Graz Univ Technol, Inst Chem & Technol Mat, Stremayrgasse 9, A-8010 Graz, Austria; [Kovalcik, Adriana] Brno Univ Technol, Dept Food Chem & Biotechnol, Fac Chem, Purkynova 118, Brno 61200, Czech Republic; [Musilova, Lenka; Mracek, Ales; Smolka, Petr; Minarik, Antonin; Ponizil, Petr] Tomas Bata Univ Zlin, Fac Technol, Dept Phys & Mat Engn, Nam TG Masaryka 275, Zlin 76001, Czech Republic; [Vicha, Robert] Tomas Bata Univ Zlin, Fac Technol, Dept Chem, Nam TG Masaryka 275, Zlin 76001, Czech Republic
utb.scopus.affiliation Centre of Polymer Systems, Tomas Bata University in Zlín, třída Tomáše Bati 5678, Zlín, Czech Republic; Institute for Chemistry and Technology of Materials, Graz University of Technology, Stremayrgasse 9, Graz, Austria; Department of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkynova 118, Brno, Czech Republic; Department of Physics and Materials Engineering, Faculty of Technology, Tomas Bata University in Zlín, nám. T.G. Masaryka 275, Zlín, Czech Republic; Department of Chemistry, Faculty of Technology, Tomas Bata University in Zlín, nám T.G. Masaryka 275, Zlín, Czech Republic
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Technology
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Department of Physics and Materials Engineering
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Department of Physics and Materials Engineering
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Department of Physics and Materials Engineering
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Department of Physics and Materials Engineering
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Department of Chemistry
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Department of Physics and Materials Engineering
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