Compositions of polyphenols in wild chive, meadow salsify, garden sorrel and ag yoncha and their anti-proliferative effect

Abstract

During past decades a lot of experimental studies shown that polyphenols have anti-carcinogenic properties have been published. Their antioxidant and tumour arresting effects have been demonstrated using both in vitro and in vivo studies many times. Aim of the present study was to investigate the content of polyphenols in edible flowers of Ag yoncha, Wild chive, Meadow salsify and Garden sorrel and their effect on proliferation activity of human hepatocellular carcinoma cells which has not been studied yet. Anti-proliferative effect was evaluated in vitro using following concentrations of polyphenols 100, 75, 50 and 25μg/ml. Also, phenolic composition was determined by the high performance liquid chromatography The present results indicate that even low concentrations of edible flowers' polyphenols inhibited cell proliferation significantly. This effect was observed at all studied edible flowers extracts and was independent on the compositions of individual polyphenols. Results indicate possible employment of studied edible flowers for prevention as well as for treatment of cancers.