Plasma treatment of biomedical materials

Junkar, Ita; Cvelbar, Uroš; Lehocký, Marián

dc.title	Plasma treatment of biomedical materials	en
dc.contributor.author	Junkar, Ita
dc.contributor.author	Cvelbar, Uroš
dc.contributor.author	Lehocký, Marián
dc.relation.ispartof	Materiali in Tehnologije
dc.identifier.issn	1580-2949 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued	2011
utb.relation.volume	45
utb.relation.issue	3
dc.citation.spage	221
dc.citation.epage	226
dc.type	article
dc.language.iso	en
dc.publisher	Institut za Kovinske Materiale in Tehnologije Ljubljana	sl
dc.relation.uri	http://mit.imt.si/Revija/mit113.html
dc.subject	plasma treatment	en
dc.subject	biocompatibility	en
dc.subject	polymer	en
dc.subject	vascular grafts	en
dc.subject	endothelia cells	en
dc.subject	platelets	en
dc.description.abstract	Surface plasma treatment techniques for modification of biomedical polymeric materials are presented. The emphasis is on the use of non-equilibrium radiofrequency (RF) oxygen and nitrogen plasma. By variation of discharge parameters (power, discharge frequency, type of gas) and plasma parameters (density of neutrals and ions, kinetic energy of electrons, gas temperature) it is possible to produce polymer surfaces with different surface properties. Already after short plasma treatment time the surface of polymeric material becomes hydrophilic. Formation of nitrogen and oxygen functional groups is observed immediately after plasma treatment. By optimisation of plasma treatment time the number of newly formed functional groups can be increased. Plasma treatment also produces morphological changes of the surface; nanohills of different shapes and height can be formed on PET surface depending on the treatment time and type of gas. Evidently the change in surface morphology affects the change in surface roughness, which increases with longer plasma treatment time. Plasma treatment influences also on the biological response, as all plasma treated surfaces exhibit improved proliferation of fibroblast and endothelia cells. The number of adherent platelets practically does not change after nitrogen plasma treatment, however much lower number of adherent platelets is observed on oxygen plasma treated surfaces.	en
utb.faculty	University Institute
dc.identifier.uri	http://hdl.handle.net/10563/1002190
utb.identifier.rivid	RIV/70883521:28610/11:43865318!RIV12-MSM-28610___
utb.identifier.obdid	43865320
utb.identifier.scopus	2-s2.0-79958004146
utb.identifier.wok	000291170700010
utb.source	j-wok
dc.date.accessioned	2011-08-16T15:06:38Z
dc.date.available	2011-08-16T15:06:38Z
dc.rights.uri	http://mit.imt.si/
dc.rights.access	openAccess
utb.ou	Centre of Polymer Systems
utb.contributor.internalauthor	Lehocký, Marián
utb.fulltext.affiliation	Ita Junkar1, Uroš Cvelbar2, Marian Lehocky3 1 Odsek za tehnologijo površin in optoelektroniko, Institut "Jožef Stefan", Jamova cesta 39, 1000 Ljubljana, Slovenija 2 Center of Excellence for Polymer Materials and Technologies, Tehnolo{ki park 24, 1000 Ljubljana, Slovenia 3 Medical Materials Research Centre, Technology Park, Tomas Bata University, Nad Ovcirnou 3685, Zlin, Czech Republic [email protected]
utb.fulltext.dates	Prejem rokopisa – received: 2011-02-15 sprejem za objavo – accepted for publication: 2011-03-06
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utb.fulltext.sponsorship	The authors acknowledge the financial support from the Ministry of Higher Education, Science and Technology of the Republic of Slovenia through the contract No. 3211-10-000057 (Center of Excellence Polymer Materials and Technologies).
utb.fulltext.projects	3211-10-000057